...义寡核苷酸的合成:参照文献[2]的方法,MMP-28反义寡核苷酸(AODN)序列为: 5′-GCCGACGCGCGCGACCATCTCGCC-3′;以正义寡核苷酸(SODN)作为对照,序列为: 5′-GGCG AGATGGTCGCGCGCGTCGGC-3′。硫代磷酸化修饰,PAGE纯化,由上海生工生物公司合成。
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RESULTS SODN inhibited the growth of CNE1 and CNE2Z cells as well as ASODN, and presented dose and time dependent manner.
结果端粒酶正义寡核苷酸与反义寡核苷酸一样可抑制鼻咽癌cne1和CNE2 Z细胞的生长，且呈剂量和时间依赖性。
Methods To set up HER-2 antisense oligodeoxynucleotides (ASODN) experimental group, sense oligodeoxynucleotides (SODN) group, folate acid (FA) group and 60Co irradiation control group.
方法实验分组如下：HER-2反义寡脱氧核苷酸组、HER-2正义寡脱氧核苷酸组、叶酸对照组和空白对照组。
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