People with the disease were often treated as social outcasts.

患有这种疾病的人常被社会摈弃。

《牛津词典》

In plain words, mistrusted and misjudged by most people they are regarded as social outcasts.

坦率地说，因为大部分人都不信任他们，冤枉了他们，所以，他们成了被社会遗弃的人。

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And strike your notions of gamers as outcasts: one researcher found that white-collar professionals who play video games are more confident and social.

最后打击一下你认为游戏者都受排斥的观念：一个研究发现玩游戏的白领专业人员要更自信和有社交能力。

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Even so, they also weren't the extreme social outcasts and loners depicted in the early days of media coverage.

CNN: Debunking the myths of Columbine, 10 years later

It's getting harder to paint the Net as an exclusive domain for geeks, social outcasts, libertarians and hate groups.

CNN: Opinion: Is the Internet maturing?

Ethnically distinct from Somalis, the Somali Bantu have always been social outcasts.

BBC: Persecuted Bantus begin new life