It is little wonder (that) she was so upset.

她如此心烦意乱，并不奇怪。

《牛津词典》

Why are you so upset and worried?

你为什么这么不安和忧虑？

youdao

He sounded so upset that Ann started to have pity on him.

他听上去非常难过，安开始同情他了。

youdao

"We must stop the shark-finning which is resulting in the death of thirty to seventy million sharks each year because that has so upset ocean ecology by the removal of these often apex, top-level predators."

VOA: special.2011.03.15

I get so upset when you just try to ignore the problem.

你都不想管这事儿，我还挺生气的。

I get so upset 实战 - SpeakingMax英语口语达人

I get so upset when you just try to avoid the problem.

你想逃避这个问题，我还挺生气的。

I get so upset 实战 - SpeakingMax英语口语达人

What I am upset about is THAT THESE TWO GUYS ARE SO UPSET ABOUT IT.

FORBES: Bans and Censures for Rattner and Rangel Respectively

This is why the public is so upset and dismayed by the Ryan plan.

FORBES: The Republicans Must Rethink Medicare Reform

"I was so upset when I saw what happened here, " says Nadia, aged 12.

BBC: NEWS | South Asia | Defying the Taliban to get an education