Likeall Made Solid pieces, this one is cut, shaped, sewn and finished by hand in artist Peter Maxwell 'slos Angeles studio.

跟Made Solid的所有产品一样，这个皮袋从切割、造型、缝制到最后完成，每一步都是在艺术家彼得·麦克斯维尔的洛杉矶工作室手工完成的。

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Children with SLOS have autism spectrum disorders and the most severely affected have birth defects, such as cleft palates, learning disabilities and heart defects.

BBC: 'No-one had heard of my boys' syndrome'

The discovery that both boys had a rare metabolic condition called Smith-Lemli-Opitz syndrome (SLOS), which results from a failure of the body to make its own cholesterol, explained many of their struggles during their early years.

BBC: 'No-one had heard of my boys' syndrome'

Dr Lloyd-Evans explains that the absence of cholesterol in the brains of SLOS sufferers means that the neurons and the central nervous system are affected, causing anything from mild personality disorders to severe malformations and multi-organ disease.

BBC: 'No-one had heard of my boys' syndrome'