Methods The healthy volunteers were divided into 6 different dose groups randomly for the clinical trial including 4 single dose groups and 2 multiple dose groups.

方法采用随机分组的观察方法，共分6个剂量组，即单次和累积给药剂量组，其中单次给药剂量组4个，累积给药剂量组2个。

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In a phase 1 trial, infected patients who got a single 100 mg dose of the compound saw their viral load drop by more than 99.9% within 24 hours.

在一个一期试验中，单一服用100 mg剂量该化合物的的感染者可见到24小时内他们的病毒负荷下降了超过99.9%。

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In a trial of 38, 546 people 60 and up, sponsored by the VA and Merck, a single dose reduced the incidence of shingles over the next three years by half and slashed severe cases of postshingles pain (usually lasting three months or more) by two-thirds, according to the results in the New England Journal of Medicine (June 2, 2005).

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