Significant diseases, especially measles, are prevalent or imminent.

严重的疾病，如风疹麻疹等流行或即将爆发。

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Diabetes is one of harming human health's significant diseases, in recent years, diabetes prevalence rate assumes year by year.

糖尿病是危害人类健康的重大疾病之一，近年来，糖尿病的患病率均呈逐年上升趋势。

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The proximity of mosquito vector breeding sites to human habitation is a significant risk factor for chikungunya as well as for other diseases that these species transmit.

蚊子滋生地邻近人类居住地，是基孔肯雅热重要危险因素，也会传播其他疾病。

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Genetic diseases also pose significant challenges in the design of clinical trials, particularly in identifying biomarkers and other surrogates for disease progression.

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Any effective "vaccine" would be a significant breakthrough in auto-immune diseases such as MS and rheumatoid arthritis.

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The diseases would have a significant impact of deaths from heart disease.

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