However, none of the organic acids showed significant alteration in the content and component under salt stress.

盐胁迫下，除了苹果酸合成酶活性上升以外，其它酶活性均无显著性变化。

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No significant alteration to these arrangements and methods shall be made without this having previously been notified to the Engineer.

在事先未通知工程师的情况下，不得对此类安排和方法进行重大修改。

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Results The created rat vascular dementia model showed significant alteration in leaning and memory function, and obvious decreased content of acetylcholine in hippocampal tissues.

结果行为学检测结果表明，血管性痴呆大鼠有明显的学习、记忆障碍，且该组大鼠海马组织乙酰胆碱含量持续降低。

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In the context of a bloated and dysfunctional health care system, this significant and immediate alteration in health insurance coverage could be very difficult for many households to absorb financially, particularly if their income falls just above the threshold for federal subsidies to purchase policies in the upcoming health insurance exchanges.

FORBES: Direct Health Care for the Uninsured