Excessive activation of KATP is now recognized as a major cause of hypotension and vascular hypo-responsiveness to catecholamine in septic shock.

目前认为。过度激活血管KATP会导致脓毒症体克时的低血压和血管对儿茶酚胺的低反应性。

youdao

However, there is controversy whether catecholamines can worsen myocardial damage in patients with septic shock because of adrenergic receptors activation.

但这类药物是否会因为肾上腺能受体的影响而加重危重状态下心肌细胞的损害，目前仍存在争议。

youdao