Granted, Mary Jane is the woman Peter married and the one he was perhaps always destined to end up with, but Gwen is one of the most important supporting characters in Spider-Man history, and she deserves to get the full attention and treatment worthy of her place in the mythos.
By injecting the orb weaver gene into the father of Mille and Muscade, Nexia bred she-goats with mammary glands able to produce the complex proteins that make up spider silk.