Seriously though, it could be really dangerous.

不过说实在的，这事说不好真的很危险。

《牛津词典》

Seriously though, open water swimming can be a wonderful activity.

说正经的，公开水域游泳可以是很爽的活动。

youdao

Though seriously ill, he still clings tenaciously to life.

他虽然病情严重，但仍顽强地活着。

《牛津词典》

Seriously though, the reasons I skipped Prometheus in the cinema was the lack of a 2D screening.

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Seriously though, only 34 percent wanted color screens?

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Seriously though -- this stuff is pretty sweet.

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