"Mind like wormwood" indicates a narrow and bending mind which is caused by self-isolation.

“蓬之心”是人们由于将自我封闭起来而形成的狭隘、“蔽于一曲”的心灵状态。

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With no proper understanding of the state of affairs, Japan is walking down a path of self-isolation.

日方的做法显然是不合时宜、不识时务地自我孤立。

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Wenders's films have always been known as "existential film" the title, for this title, Wenders's own answer is "Self-isolation from the agency is a common social phenomenon."

文德斯的电影也一贯被冠以“存在主义电影”的雅号，对于这个名称，文德斯自己的答案是“脱离社自我封闭，是一个普遍的社会现象。”

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But if I'm honest with myself, my self-imposed isolation from other moms has left me feeling a little alone in the new-mommy experience.

CNN: A kind of courtship: Finding a mom friend in the big city

It has not, so far, evidently suffered economically from this self-imposed isolation.

ECONOMIST: Christoph Blocher, ascendant Swiss populist

Serbia, for its part, has to choose if it wants to stay on the democratic path or head into self-imposed isolation, officials say.

ECONOMIST: Enlargement enriches old as well as new members