In many protein aggregation diseases, incorrectly folded proteins self-associate, forming fiber-like aggregates that cause brain cell death and dementia.

在很多蛋白质凝聚的疾病中，错误折叠的蛋白自我结合，形成纤维样的凝集体，从而导致脑细胞死亡和老年痴呆。

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And that ethic, that kind of honor and self-discipline and integrity -- those are the values that we associate with small towns like this one.

WHITEHOUSE: Rural Economic Forum: Opening Remarks

And some people are self-absorbed, lack personal goals, associate with the wrong crowd in the wrong places, or constantly blame others for failing to get ahead in life, rather than taking the right steps to escape from this context.

FORBES: Beyond The Secret: Change Your Life in Five Simple Steps

"Nothing could be less content-neutral than doing self-help law, " says Stephen Elias, associate publisher at Nolo Press, a privately held Berkeley, Calif. book and software company that publishes WillMaker, Small Business Legal Pro and other self-help guides.

FORBES: Arrest that software!