The risk of a second cancer increased with the number of first degree relatives with cancer.

患第二种癌症的风险随着一等亲患癌症的人数增加而增加。

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Second-degree relatives are aunts and uncles, nephews and nieces, grandparents and grandchildren.

二级亲属包括伯姑舅姨、侄子女和祖父母。

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And, while rates of obesity dropped substantially between first and second degree relatives of obese patients without the gene mutations, this was far less obvious among relatives of those who were carriers.

BBC: NEWS | Health | Faulty gene link to obesity risk