Even high-priced commodities like spices had to be transported in large bulk in order to justify the expense and trouble of sailing around the African continent all the way to India and China.

即使像香料这样的高价商品，也必须大量运输，以证明环绕非洲大陆航行到印度和中国的费用和不便是合理的。

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So, basically, in order to move, a cell climbs hand-over-hand along the extracellular matrix until it reaches a blood or lymphatic vessel and penetrates it. From there, it's smooth sailing.

基本而言，细胞顺着细胞外基质移动，一旦发现血管或淋巴管，穿透血管和淋巴管，这样就畅通无阻了。

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To turn a sailing ship so that its bow heads into the wind and the ship lies motionless except for drifting, in order to meet a storm.

将帆船顶风停船：转动正在航行的船只使船头迎风，船除了漂泊外一动也不动地停在水中，以便迎接暴风。

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Howard's 20-foot boat has not only been re-fitted in order to make sailing easier, it is also equipped with essential technologies to ensure the safety of both Howard and other sailors, including an Automatic Identification System (AIS), which alerts Howard to ships within a 50-mile radius.

CNN: 'Blind' man to sail around the world alone

Costa Cruises boss Pier Luigi Foschi accused Capt Francesco Schettino of sailing too close to a nearby island in order to show the ship to locals.

BBC: Costa Concordia cruise ship captain 'went off course'