The progressive result is an accumulation of fatty deposits called plaque that can rupture or have their caps shear off, causing clots that lead to heart attacks.

Donohue博士说，进一步恶化的结果是称之为血斑的脂肪沉积开始积累、破裂、剥落，最后形成导致心脏病发作的血栓。

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Over time, the buildup of plaque deposits can rupture and cause total blockage of the blood flow to the heart.

久而久之，血小板沉积物逐渐积累，会导致流往心脏的血液完全阻塞。

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Once that plaque builds up, it can rupture and completely block the artery, cutting off the blood supply to your heart.

一旦斑块堆积，则会损伤并完全阻塞动脉，造成心脏缺血。

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These high leukotriene levels, DeCode researchers believe, inflame artery walls, increasing the odds that arterial plaques will suddenly rupture and cause heart attacks or strokes.

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Just last month, researchers led by Armin Arbab-Zadeh of Johns Hopkins University School of Medicine in Baltimore published a comprehensive review of the biology of heart attacks in the journal Circulation, which said that vulnerable plaques often rupture without causing a heart attack and that a "perfect storm" of other conditions is required before one occurs.

WSJ: Predicting Who Will Have Heart Attacks

New catheter-based imagers aim to improve IVUS by letting doctors distinguish stable plaque, safely ensconced in scar tissue, from the inflamed plaque that is more likely to rupture and trigger a heart attack.

FORBES: Peeking at Plaque