The young people run around kicking a ball, wearing themselves out.

这些年轻人四处跑动踢球，把自己弄得筋疲力尽。

《柯林斯英汉双解大词典》

A lot of people want to work for themselves, but when they find out they have to run a business, they are surprised.

许多人想要做自己的老板，但当他们发现必须自己经营企业时，又很震惊。

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In case you missed 60 Minutes on Sunday, I recommend this segment about an innovative program to help people who have been unemployed so long that their jobless benefits have run out, and their faith in themselves has crumbled.

FORBES: Hope For The Long-Term Jobless?

Cancers are driven to make copies of themselves, however, if cancerous cells run out of the building blocks of their DNA they develop "DNA replication stress".

BBC: Thriving cancer's 'chaos' explained

Thus, those states claiming that they are cutting fat and waste are actually setting the stage for the impoverishment of their citizenry and a long-run decline in the revenues available to pull themselves back out of this hole.

FORBES: Why US education deserves our praise (and funding)