Don't give up whenever you run into difficulties on your way to success.

在通往成功的道路上，无论何时你遇到困难都不要放弃。

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When the economy slows, companies run into difficulties, businesses scale back their workforce, and layoffs increase.

在经济低迷时期，公司遭遇到难关，企业缩减员工，加快了裁员。

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Roberto Mancini, the City manager, wants a striker and has run into difficulties with Wolfsburg over the valuation of Edin Dzeko.

曼城的主教练曼奇尼想要一个前锋，而与沃尔夫斯堡关于球员埃丁-泽科的转会费谈判陷入僵局。

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Both players run into difficulties on the par-four 15th, with Garcia finding two bunkers with his first two shots.

BBC: Sunday at Wentworth

The transformation began with the purchase in 1995 of Franchi, another gunmaker in Gardone Val Trompia that had run into difficulties.

ECONOMIST: Beretta

This low capital approach has run into difficulties when applied to clean energy as nicely detailed in this Harvard Business School review.

FORBES: Why Venture Capital Is Weak Fuel For Clean Energy Startups