Results (1) The 170 site of HPVI6E6 gene was chosen as cleavage site. The hammerhead ribozyme has two arms of 9 nt.
结果 1、选择E6基因的170位为切割位点,设计锤头状的核酶,两侧的结合臂各为9个碱基。
参考来源 - 抗人乳头瘤病毒16型E6基因核酶对宫颈癌细胞株表型和基因调控的影响The ideal ribozyme should satisfy with requires of highly catalytic efficiency, well specificity and stabilization.
理想的核酶应满足高效、特异 、稳定的要求。
参考来源 - 分裂β·2,447,543篇论文数据,部分数据来源于NoteExpress
以上来源于: WordNet
N an RNA molecule capable of catalysing a chemical reaction, usually the cleavage of another RNA molecule 核酶
Ribozyme is a kind of catalytic nucleic acid molecules.
核酶是一类具有催化功能的核酸分子。
The ideal ribozyme should satisfy with requires of highly catalytic efficiency, well specificity and stabilization.
理想的核酶应满足高效、特异、稳定的要求。
Conclusion Ribozyme targeting cyclin Dl may effectively inhibit cyclin D1 expression and activation in the HSC T6 cell line.
结论载体表达的特异性核酶能有效地抑制HSC的细胞周期蛋白d1的表达和激活。
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