12 兔出血病病毒 兔出血病病毒(Rabbit hemorrhagic disease virus ,RHDV)主要引起兔致死性肝病。其基因 组全含2个ORF ,其中ORF1编码主要结构蛋白VP60。
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RHDV antigen 兔出血症病毒抗原
RHDV antigen was not detected in sera, liver, kidney and spleen.
血清及RHDV的靶器官肝、脾、肾中均未检测出RHDV抗原。
After manifestative stage of the disease RHDV gradually diffused from nucleus into cytoplasm and reached a maximum in cytoplasm at agonal stage.
疾病后期，核内的RHDV颗粒通过破损的核膜或核崩解向细胞浆扩散。
The results showed that RHDV was the pantropic virus injuring most tissues and cells, but the main injured organ was liver, the principal target cells were hepatocytes and endothelial cells.
结果表明RHDV是侵害多种组织细胞的泛嗜性病毒，但其主侵器官是肝脏，主要靶细胞是肝细胞及血管内皮细胞。
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