同一剂量的药物,在机体休息-活动周期(rest-activity cycle)的 不同时间给药,产生不同的疗效,在周期的某一位相对机体产生有益 作用,而在另一位相则产生有害作用,甚至可以致死。
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Their sleep/wake cycle lengthened suggesting the brain mechanism that controls the timing of activity and rest had been affected.
它们的作息周期变长，表明控制作息时间的大脑机能受到影响。
However, a comparison of the EKG measured during rest and the EKG measured after mild exercise may indicate the changes, if any, that take place in the cycle of heart contractions due to activity.
然而，如果由于活动引起心脏收缩循环中发生任何变化，休息时测量的EKG与轻微锻炼后测量的EKG的对照却可以将它表示出来。
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