Method Introducing aminoglycoside antibiotic resistant mutation into a pyrrolnitrin producer to increase pyrrolnitrin productivity.

方法在硝吡咯假单胞菌中引入氨基糖苷类抗生素抗性突变，以提高硝吡咯菌素的生产能力。

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Objective To investigate the relationship of HBV Lumivudine resistant and HBV genotypes and basic core promoter (BCP) mutation.

目的了解拉米夫定耐药与HBV基因型及HBV基本核心启动子(BCP)突变之间的关系。

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The results suggested that AIV 178 isolate was amantadine resistant, and the position 31 amino acid point mutation in M2 protein may confer the resistance.

结果表明AIV 178分离株具有对金刚烷胺的耐药性，而且M2蛋白的第31位氨基酸突变可能与此有关。

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The problem: His leukemia cells contained a mutation that made them resistant to Gleevec's effect.

FORBES: The Race Is On

There is another route being considered - involving a rare mutation that leaves people resistant to HIV infection.

BBC: Analysis: A cure for HIV?