The pathophysiological basis of chronic pain syndromes remains poorly defined.

慢性疼痛综合征的病理生理学基础仍较难定义。

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However, the basic molecular pathogenesis of epigenetics in MDS remains poorly understood.

然而，人们对MDS的表观遗传学基础分子发病机制还知之甚少。

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Which patients would specifically benefit from early combination therapy also remains poorly defined.

究竟哪些患者尤其适合早期联合治疗仍然没有完全确定。

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More important, Hawaii's openly gay community remains fledgling and poorly organized.

CNN: For better or worse

Other critics - including the main opposition Bharatiya Janata Party - said that Mr Mukherjee's remarks were particularly poorly timed, as the 23-year-old rape victim remains on life support in a Singapore hospital.

BBC: India president's son apologises over rape comments