Down-regulated activity and absolute or relative absence of growth factors and their receptors in diabetic foot ulcer is the pathophysiologic basis of wound hard to heal.

溃疡创面局部生长因子及受体活性下降和数量的绝对或相对缺乏是其难以愈合的病理生理基础。

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PDH activity is regulated by phosphorylation and dephosphorylation (3).

PDH的活性可以被磷酸化和去磷酸化调节(3)。

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Under normal conditions, the activity of the NMDA receptors is tightly regulated to prevent nerve cells from becoming overloaded with calcium.

正常情况下，NMDA受体活性较低从而保证神经细胞不会出现钙超载。

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This not only regulated activity in a tightly planned economy, but was also a vital link in the chain of social control.

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The Court today holds that our Constitution protects us from federal regulation under the Commerce Clause so long as we abstain from the regulated activity.

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Hiring a skilled foreign national is already a highly regulated activity.

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