He went ahead and did it, regardless of the consequences.

他说干就干了，没有考虑后果。

《牛津词典》

For addicted individuals, eating becomes compulsive, regardless of negative health or societal consequences.

对于上瘾的个体，吃变成了强迫性的，不顾一切的负面性健康和社会结果。

youdao

I believe - heroes are the people who do what has to be done when it needs to be done, regardless of the consequences.

我相信—英雄就是，不管后果如何，当需要做一件事的时候就勇往直前义无反顾的去做这件事。

youdao

Categorical moral reasoning locates morality in certain absolute moral requirements, certain categorical duties and rights, regardless of the consequences.

绝对主义道德推理认为,是否道德取决于特定的绝对道德准则，取决于绝对明确的义务与权利，而不管后果如何。

耶鲁公开课 - 公正课程节选

Our Western heritage has been one of control, of man against nature, of man needing to tame nature, and create as his likes and as his needs dictate regardless of consequences.

BBC: reith feed

Politicians from Washington to Beijing are being pressed to help troubled industries, regardless of the consequences for trade.

ECONOMIST: Trade and the world economy

Doing what is right regardless of the consequences: a John Hancock moment.

FORBES: This Is Wisconsin Gov. Scott Walker's John Hancock Moment