位点特异性重组系统均只包含两个部分:重组酶(Recombinase)和该重组酶能特 异识别的位点(Recognitionsit曲,重组酶专一性地识别并介导两个同向特异识别序列 发生重组,形成环状DNA并脱离染...
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Cre recombinase 重组酶
FLP recombinase 重组酶 ; FLP重组酶
dna recombinase cre dna重组酶cre
cell-permeable cre recombinase 细胞可透过性cre重组酶
tyrosine recombinase 酪氨酸重组酶
red recombinase red重组酶
recombinase FLP 重组酶FLP
vdj recombinase VDJ重组酶
以上来源于: WordNet
"The advantage of a site-specific recombinase is that the enzyme does everything," says Stark, who is also investigating the potential of ZFRs in genetic engineering.
“位点专一重组酶的优势就是酶做了所有的事。”斯达克说,他同时还在调查研究Z FR在遗传工程学中的潜力。
When the intended gene, which would have been inserted at the same time, comes along, the recombinase recognises it, and binds the DNA to the ends, repairing the break (see diagram).
当预期的可同时植入的基因出现时,承认它的重组酶,会把它固定在DNA的两端,开始修补DNA(见图)。
As proof of principle, Barbas's team has taken human cells and inserted a gene that their ZFR would recognise. They then used the recombinase to insert the gene into the cells' genome.
巴尔·巴斯的团队为了证实这一原理,他们在人体细胞中植入了他们的ZFR能辨识的基因,然后利用重组酶将基因植入到基因组细胞中。
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