Ranolazine dihydrochloride 盐酸雷诺嗪
Ranolazine HCl 盐酸雷诺嗪 ; 雷诺嗪
Ranolazine Hydrochloride 盐酸雷诺嗪
Ranolazine N-oxide 雷诺拉嗪N氧化物
Ranolazine glucuronide 雷诺拉嗪葡糖苷酸
Ranolazine impurity D 雷诺嗪杂质D
Intermediate of Ranolazine 雷诺嗪中间体
Ranolazine Related Compound B 雷诺嗪相关物质B
Ranolazine Related Compound A 雷诺嗪相关物质A
Adrenergic beta receptor antagonists,trimetazidine,ranolazine,perhexiline and metformin were currently paid more attention in the study of metabolic therapy for heart failure.
肾上腺素β受体拮抗药、曲美他嗪、雷诺嗪、哌克昔林、二甲双哌等是目前心力衰竭代谢治疗中研究最多的药物。
参考来源 - 心力衰竭的代谢治疗进展So it is necessary to find a new feasible process of synthesizing Ranolazine.
因此对文献报道的雷诺嗪的合成工艺进行改进是有必要的。
参考来源 - 雷诺嗪和类似物的合成及其抗心绞痛活性研究·2,447,543篇论文数据,部分数据来源于NoteExpress
OBJECTIVE To synthesize Ranolazine and improve the synthetic process.
目的合成雷诺嗪并进行工艺改进。
The ranolazine works by blocking what is called delayed inward sodium current.
雷诺嗪的作用机制是阻断迟发性钠离子内流。
METHODS Ranolazine was synthesized by using 2, 6-dimethylaniline and guaiacol as the starting material fellewed by 4 step reactions.
方法以2 ,6 -二甲基苯胺、愈创木酚为原料,经酰化、烃化等4步反应制得雷诺嗪。
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