site-directed random mutation 定点随机突变
random mutation hill climbing 随机变异爬山
neutral mutation random drift hypothesis 中性突变漂变假说
neutral mutation-random drift theory 中性突变随机漂变学说
random point mutation 随机点突变
HI47 was a murine anti-CD20 antibody, developed in 1990 by the institute of Hematology. Using HI47 as parent,we had already constructed its Fab' by random mutation,with the mutant strain named CD20-7.
HI47是我所于1990研制成功的抗CD20鼠源性单克隆抗体,CD20-7是以HI47为母体,通过随机突变的方法,得到的Fab’的高表达突变株。
参考来源 - 抗CD20嵌合抗体突变体HI47F(ab')The strategy of this engineering is to simulate the process of protein molecular natural evolution,to introduce the random mutation in the gene of target protein,and to select the excellent character of mutant.
该工程策略是:模拟蛋白质分子自然进化过程,在目的蛋白质的基因中引入随机突变,然后筛选出性状优良的突变体。
参考来源 - 枯草杆菌安舒克栓酶随机突变、筛选及其部分性质研究·2,447,543篇论文数据,部分数据来源于NoteExpress
BIOLOGICAL evolution happens by random mutation and selection.
生物进化是由随机“突变”和“选择”产生的。
The dynamic Differential Evolution (DE) algorithm with random mutation was proposed.
提出一种带有随机变异的动态差分进化算法。
Merging the parents' DNA, and then applying a random mutation to the merged DNA simulates procreation.
合并双亲的DNA,对合并后的DNA应用随机变异以模拟繁衍。
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