Soon you begin to question whether violating the client-stateless-server constraint was such a good idea after all.

很快您就会质疑，违背客户机-无状态-服务器约束是否真的是一个好主意。

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Wildcards - the funky question marks where a type parameter should go - are a means of expressing a type constraint in terms of an unknown type.

通配符—使用一个奇怪的问号表示类型参数—是一种表示未知类型的类型约束的方法。

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So, how to construct a efficient mechanism to motivate and to constraint fund managers so that they can work hard for the funds investors is an important question.

因此，如何建立一个有效的机制，来激励约束基金公司和基金经理，使他们更好地为广大投资者服务，就成为一个引人注目的问题。

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Until recently, they have had to feed their bacteria with the unnatural amino acid in question, but in one case they have managed to overcome even that constraint.

ECONOMIST: Chemists are trying to synthesise new varieties of life