Expression of the PTEN tumor suppressor is frequently lost in breast cancer in the absence of mutation or promoter methylation through as yet undetermined mechanisms.
PTEN肿瘤抑制因子在乳腺癌中虽常呈失表达，但并不是通过基因突变或促进子甲基化而实现的，因此其失表达的机制还不清楚。
To study the relationships between the expression level of PTEN gene, gene mutation and occurrence and development of glioma.
目的：探讨pten基因表达水平及其基因突变与脑胶质瘤的发生及恶性进展的关联性。
应用推荐