Well, there is a reference to the pain of the test itself, presumably the PSA (Prostate Specific Antigen) test.

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In the other study, conducted at multiple sites in Europe, researchers found PSA testing lowered prostate cancer-related deaths by 20 percent.

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In May 2012, the U.S. Preventive Services Task Force recommended against routine PSA screening (Prostate-Specific Antigen test to screen Prostate cancer) before being diagnosed as it did not benefit patients.

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