The molecule is part of a large family of proteins called G-protein coupled receptors (GPCRs).

这一分子属于名为“G蛋白伴随受体”的蛋白家族。

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G-protein Coupled Receptors (GPCRs) belong to one of the largest superfamilies of membrane proteins and are important targets for drug design.

蛋白偶联受体属于跨膜蛋白的大家族，在药物设计中起着很重要的作用。

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Lysophosphatidic acid (LPA) is a bioactive phospholipid mediator, which elicits a variety of biological functions mainly, through G-protein coupled receptors.

溶血磷脂酸(LPA)是一种生物活性磷脂介质，主要通过G蛋白偶联受体发挥多种生物学功能。

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Peroxynitrites contribute to the hyperphosphorylation of tau proteins by oxidating g-protein coupled receptors and trysoine kinase receptors preventing protein kinase C and AKT from inactivating the enzyme GSK3 which is necessary to prevent the hyperphosphorylation of tau proteins.

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Noting that its basic structure resembled that of other receptors, he also came to understand that there exists an entire family of similar receptors, now widely known as G-protein-coupled receptors, or GPCRs.

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Cadus is using yeast to identify a class of proteins known as G protein-coupled receptors.

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