...细胞中的蛋白酶体(proteasomes)是所有真核生物中负责清除细胞内垃圾的除溶酶体以外的水解体系,能够从碱性、酸性和中性氨基酸的羧基侧水解多种与遍在蛋白连接的...
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ubiquitin-proteasomes pathway 泛素 ; 蛋白酶复合体通路 ; 体通路
proteasomes overview 蛋白酶体
Proteasomes inhibitor 蛋白酶体抑制剂
dysfunction of proteasomes 蛋白酶体功能障碍
Applications of several perspective drugs such as Thalidomide, proteasomes inhibitor, arsenical and other agents bring galactic breakthrough to the treatments of MM.
一些有前景的药物如沙利度胺、蛋白酶体抑制剂、砷剂等的应用使MM的治疗得到了极大的突破。
By carefully measuring the rate at which proteasomes laboured, she found a clear correlation: as the clumps of prions in the sample got bigger, the proteasomes slowed down.
通过测试这些水解酶的工作速率,她发现了一个清晰的关系:当标本中的朊病毒团变大时水解酶的工作便慢了下来。
However, the Belgium/USA team has found that proteasomes can also splice the peptide fragments together in a reverse order to that encoded by the proteins DNA sequence template.
然而,比利时/美国的一个研究小组发现蛋白酶体还可以拼接这些肽段,拼接的方向与编码这些蛋白质的DNA模版链方向相反。
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