To be effective, and to avoid the development of resistance in bacteria, prophylactic antibiotic therapy is used for only a short time.
抗生素预防用药只能短期应用，以达到药物疗效及避免细菌耐药性产生。
Necessary preoperative respiratory preparation, drainage of secretion in airway and prophylactic antibiotic use during operation should be performed.
术前进行必要的呼吸道准备，术中吸除气道分泌物，预防性应用抗生素。
Conclusions Currently available evidence from RCTs does not support prophylactic antibiotic use in patients with BSF, whether there is evidence of CSF leakage or not.
结论现有的随机对照试验证据并不支持对颅底骨折患者预防性使用抗生素，无论其有无脑脊液漏的迹象。
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