Their general characteristics are of obvious progressive metamorphism, with the heat flow from mantle as the essential factor and a collision orogenic belt to be the tectonic setting.
其共同特征是：具明显的递增变质现象，以地幔热流上升为主要因素，构造背景为碰撞造山。
The overexpression of the epidermal growth factor receptor and its ligands correlates with rapidly progressive disease and resistance to chemotherapy.
表皮生长因子受体（EGFR）及其配体的过表达与疾病的迅速进展和对化疗的耐药有密切的联系。
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