Wnt target genes,including the way the cell cycle and apoptosis-related genes (such as c-myc,cyclin D1),growth factors(such as VEGF,gastrin,HGF,c-met),in tumor progression factor(such as MMP7,MMP26,CD44,etc. ),transcription factors (such as ITF2) and other target genes(such as COX-2).
Wnt途径的靶基因包括细胞周期和凋亡相关基因(如c-myc、cyclinD1)、生长因子(如VEGF、胃泌素、HGF、c-met)、参与肿瘤进展因子(如MMP7、MMP26、CD44等)、转录因子(如ITF2)及其他靶基因(如COX-2)。
参考来源 - β·2,447,543篇论文数据，部分数据来源于NoteExpress
As a critical factor of telomerase activity, much progression has been achieved in the study of regulation of human telomerase reverse transcriptase, but the detail mechanism is still not clear.
作为端粒酶活性的关键决定因子，端粒酶逆转录酶的调控研究已取得了重大进展，但具体机制仍不清楚。
CONCLUSION: TFPI acted as an inhibitor of tissue factor pathway reflected the vascular endothelial injury and the states of coagulation indirectly in unstable angina progression.
结论：组织因子途径抑制物作为组织因子途径凝血过程的抑制物，间接反应了不稳定心绞痛发作过程中血管内皮的损伤和凝血状态。
A number of studies have provided evidence that apoptosis might be an important factor in the progression of tissue damage resulting from cerebral ischemia.
越来越多的研究证实，凋亡在轻、中度暂时性脑缺血损伤所致的神经细胞迟发性死亡过程中起重要作用。
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