There have been some indications that extra protein makes the kidneys work harder, which could be problematic for individuals with a history of kidney disease.

有一些迹象表明，过量的蛋白质会加重肾脏负担，这对有肾脏病史的人来说可能是个问题。

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Nothing is more problematic for a small group of quite different, unique individuals than to live in close quarters, in close harmony with each other.

让一小群差异巨大， 个性十足的人和睦相处，紧邻而居是一件非常困难的事情。

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They said "problematic individuals" could be relocated to other territories, but as the availability of these territories lessened killing some beavers may be necessary, the report said.

BBC: Beaver killing may be necessary in future, SNH report says

These decisions, if caught in audits or as a result of individuals sharing pay data, can lead to lawsuits that prove to be very problematic for organizations.

FORBES: Pay Secrecy: Why Bother?

Meanwhile, congressional efforts to encourage wealthy individuals to purchase low-income housing through the passive-loss provision had proven problematic as investors allowed their properties to decline to capture a greater tax write-off.

FORBES: For the 21st Century, a Network of Beneficial Philanthropy and Corporate Citizenship