Objective: To study the localization and in vitro culture of human embryonic primordial germ cell(PGC) during different stages of embryogenesis.

目的：对不同发育阶段的人胚胎原始生殖细胞（PGC）进行定位并比较其体外培养的差异。

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Here, we show that removing the translational repressor Nanos from either GSCs or their precursors, the primordial germ cells (PGCs), causes both cell types to differentiate into germline cysts.

作者表明从gsc或者其前体原始生殖系细胞(PGCs)去除翻译抑制物nan os将使两种细胞分化成生殖系包囊。

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The work by Yamanaka, Melton and Srivastava upended conventional thinking that cell development proceeds in one direction, moving step-by-step from primordial stem cells to fully differentiated adult cells.

FORBES: Cells Get a Makeover, Cancer Follows: A Path to New Therapies (and a Warning to Stem Cell Alchemists)