Objective: To study the localization and in vitro culture of human embryonic primordial germ cell(PGC) during different stages of embryogenesis.

目的：对不同发育阶段的人胚胎原始生殖细胞（PGC）进行定位并比较其体外培养的差异。

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Embryonic stem cell is a kind of undifferentiated pluripotent stem cell, which stems from pr Eimplantation ICM or early fetus primordial germ cell.

胚胎干细胞是来源于附植前胚胎的内细胞团或附植后胎儿的原始生殖细胞具有发育全能性的细胞。

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Here, we show that removing the translational repressor Nanos from either GSCs or their precursors, the primordial germ cells (PGCs), causes both cell types to differentiate into germline cysts.

作者表明从gsc或者其前体原始生殖系细胞(PGCs)去除翻译抑制物nan os将使两种细胞分化成生殖系包囊。

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The work by Yamanaka, Melton and Srivastava upended conventional thinking that cell development proceeds in one direction, moving step-by-step from primordial stem cells to fully differentiated adult cells.

FORBES: Cells Get a Makeover, Cancer Follows: A Path to New Therapies (and a Warning to Stem Cell Alchemists)