细胞在有丝分裂的末期及 G1 期里拥有一段 Cdk 活性较低的时期对于在复制起源上形成预先复制复合物（pre-RCs）是至关 重的，DNA 聚合酶在 S 相中就是在复制起源上开始 DNA 合成的。
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RC pre-stress 钢筋混凝土预应力
This complex is also a key component of the pre-replication complex (pre-RC) (reviewed in 1).
该复合体也是前复制复合体(pre - RC)的关键组成部分(回顾1)。
The MCM complex is thought to be the replicative helicase, and formation of the pre-RC is referred to as chromatin licensing.
MCM复合体被认为是一种复制解旋酶，而pre-RC的形成参与染色质许可。
MCM proteins are removed during DNA replication, causing chromatin to become unlicensed through inhibition of pre-RC reformation.
DNA复制时m CM蛋白被清除，通过pre - RC重构的抑制引起染色质未识别化。
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