Some of the reasons are due to the misuse of statistics and poor study design, but what Ioannidis and others now looking at this problem also point to are the social and political factors.
其中部分原因在于，统计数据的错误使用和蹩脚的试验设计。
But the method of its design analysis is not perfect yet, and the study on its reliability, deformation and displacement is also very poor.
但目前土钉支护结构的设计分析方法仍不够完善，对其可靠性、变形位移计算的研究也很不足。
The principal question in drug design is how to study the ligand-binding sites and others because of the poor structure information.
如何在生物胺受体结构数据严重匮乏的基础上研究受体的配基结合位点及其它功能位点，已成为药物设计中的关键问题。
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