On the other hand, the polyene region corresponding polyketide synthases evolved by intra-gene duplication, and the different number of duplications will lead to different kinds of polyene macrolide antibiotics which have different anfungal activities.
另一方面,多烯部分对应的聚酮合酶的主要进化方式为基因内部复制,复制数量的不同导致生成不同种类的,具有不同抗真菌活性的多烯大环内酯类抗生素。
参考来源 - 聚酮合酶数据库初步构建及多烯类聚酮合酶系统发育分析Streptolydigin produced by Streptomyces lydicus AS4.2501 was used as an example to study the effects of typeⅡpolyketide pathway diruption on streptolydigin production.
本文以利迪链霉菌AS4.2501中所产生的利迪链菌素为例,研究了Ⅱ型聚酮途径阻断对利迪链菌素生产的影响。
参考来源 - 菌株鉴定和Ⅱ型聚酮途径阻断对利迪链菌素生产的影响Proved by a large number of experiments,fitting precursors can effectively increase the yields of the polyketide compounds.
大量实验表明,适宜的前体能有效地增加聚酮类化合物的产量。
参考来源 - 基于代谢途径的前体对美伐他汀生物合成的影响·2,447,543篇论文数据，部分数据来源于NoteExpress
以上来源于: WordNet
So the polyketide pathway was presumed to be the main biosynthetic pathway of antibiotic AGPM.
所以聚酮途径被认为是抗生素agpm合成的主要途径。
So the polyketide pathway is presumed to be the main biosynthetic pathway of antibiotic monascus pigments.
所以聚酮途径被认为是红曲色素合成的主要途径。
Besides, these compounds have the same character that all can be transformed to precursors of polyketide biosynthesis.
而且它们都具有转化为聚酮合成前体的共同特征。
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