Objective: To observe the expression of poly (ADP-ribose) polymerase (PARP) in focal cerebral ischemia with reperfusion injury and explore the role of PARP in apoptosis.

目的观察多聚ADP 核糖聚合酶（PARP）在脑缺血再灌流损伤中的表达，探讨PARP在细胞凋亡中的作用。

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Inhibition of poly (ADP-ribose) polymerase has preventive and therapeutic effects on the treatment of shock and ischemia-reperfusion injury.

抑制聚腺苷二磷酸核糖聚合酶对休克和缺血再灌注损伤有良好的防治作用。

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The cleavage of Poly(ADP ribose)polymerase(PARP) is an molecular event of the activation of cysteine protease, and it is also an early molecular marker of apoptosis .

的蛋白酶解为半胱氨酸蛋白酶激活的分子事件，是细胞程序死亡的一个早期分子标志。

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By blocking these errant molecules, D-serine and poly ADP-ribose polymerase (PARP), researchers may be able to stop brain cells from dying while avoiding the toxic side effects that have plagued previous experimental treatments.

FORBES: Repairing The Brain

By blocking these errant molecules, called D-serine and poly ADP-ribose polymerase, known as PARP, researchers may be able to stop brain cells from dying, while avoiding the toxic side effects that have plagued previous experimental treatments.

FORBES: Repairing The Brain

Gleason also cites a new class of drugs known as PARP (poly ADP-ribose polymerase) inhibitors, which appear to be highly effective in treating breast cancer patients with certain mutations, and finally the sale of new products that could earn new markets.

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