AIM: To study the effect of phenylmethylsulfonyl fluoride (PMSF), a phospholipase C inhibitor, on ischemic injury to brain mitochondria in rats.
目的：研究磷脂酶C抑制剂PMSF在缺血性脑线粒体损伤中的作用。
Irreversible inhibitor of Thrombin and other serine proteases. Inhibits by acylation of the active site of the enzyme. Much less toxic than PMSF and DFP.
凝血酶及其他丝氨酸蛋白酶的不可逆抑制剂，将活性位点酰基化。比PMSF和DF P毒性小得多。
PMSF completely inhibited the fibrinolytic activity, but EDTA and EGTA exerted little effect on it. These results demonstrate that DFE is a serine protease.
PMSF和盐酸苯甲醚能抑制其纤溶活性，而EDTA和EGTA不能抑制，表明该酶是一种丝氨酸蛋白酶。
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