Abstract: In this paper, the existing literature on the basis of a brief description of the antiepileptic drug therapy, with a focus on antiepileptic drug (S) -2 - ethyl -2 - O -1 - pyrrolidine acetamide Technology. Screening for 2 - bromo-butyric acid as the starting material, after ammonolysis, esterification, ester amine solution, split, five-step cyclization reaction Levetiracetam. Methods used in esterification HCL / methanol and dichloro-sulfoxide and sulfuric acid to carry out experimental research aminate methanol saturated amines were used, plus salt, add water, three options to conduct experiments. Resolution of the use of non-resolution of enantiomers methods used in organic solvents tartaric acid for the separation agent, to be S-type. At the same time, this paper also split the R-isomer of racemic to change and re-recovery. Another direct use of this experiment (S )-(+)- 2 - tartaric acid amide ammonium salt hybroxybutyric cyclization experiments skip the first preparation of (S )-(+)- 2 - ammonia hybroxybutyric amide hydrochloride, and then related Preparation of Levetiracetam ring step. The synthetic route for the 25% overall yield. The process line is simple, low cost, high yield, large-scale production can be industrialized.
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green salt plus magnesium blend 四氟化铀与镁的混合物
Objective To observe the therapeutic effect of acupuncture plus salt partitioned moxibustion at Shenque (CV 8) on chloasma.
目的:观察针刺加神阙隔盐灸治疗黄褐斑的临床疗效。
Conclusion Acupuncture plus salt partitioned moxibustion at Shenque (CV 8) is a safe and convenient therapy with a remarkable effect for chloasma.
结论:针刺加神阙隔盐灸对黄褐斑是一种安全有效的治疗方法。
When you buy a pre-made sandwich, you're really just paying for its elaborate packaging — plus a whole lot of salt, fat, and unnecessary additives.
当您买回一个成品三明治, 您只不过是买了一个精致的包装—外加上很多盐、油脂和多余的添加剂。
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