The R plasmid curing experiment was performed in Shigella strain, F_(13), which used as a target bacteria bearing R plasmid with Huangqin, a traditional chinese herb, as a elimination agent in vitro.
以携带R质粒的痢疾杆菌F_（13）株为靶细菌，以黄芩甙作为R质粒消除剂，进行R质粒体外消除试验。
Besides the character of host strains and the molecular weight of the plasmid, the efficiency of curing was also related to the concentrations of curing agents and the time of treatment.
除宿主菌的特性及其所含质粒分子量大小之外，消除率还与消除剂浓度、作用时间有关。嵌合染料适用于消除大肠杆菌中的质粒。
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