Results:1、 p16 gene hypermethylation in SLE patients was showen by plasma DNA detection. (1)There was a significant difference between SLE patients(29/45, 64.44%) and healthy individuals(1/20, 5%) (x~2=19.687~b; p=0, p<0.001; OR=34.44, 95%CI 19.25 ~ 49.63) .
结果1、SLE患者血浆DNA中p16基因启动子呈现高甲基化状态:(1)SLE组中p16基因启动子呈甲基化状态者占64.44%(29/45),而健康对照组中只有1名检测到p16基因甲基化(1/20,5%),两组间差异具有统计学意义(X~2=19.687~b,p<0.001;OR=34.44;95%CI19.25~49.63)。
参考来源 - 系统性红斑狼疮患者DNA甲基化状态与趋化因子受体表达水平的研究The research of circulating plasma DNA and matched paraffin tumor tissue from breast cancer patientsin our experiment confirmed that same characteristic between plasma DNA and tumor tissue.
通过对乳腺癌患者血浆循环核酸和相应石蜡肿瘤组织的研究,证实了血浆循环核酸与肿瘤组织具有一致性。
参考来源 - 乳腺癌患者循环血浆中线粒体基因突变的临床研究·2,447,543篇论文数据,部分数据来源于NoteExpress
Objective: to explore the possibility of plasma DNA in the use of fluorescent quantitative analysis of chimerism after hematopoietic stem cell transplantation.
目的:探讨血浆DNA在造血干细胞移植术后嵌合体荧光定量分析中应用的可行性。
Conclusion The plasma DNA level may have a potential use in early diagnosis and serve as a predict marker for metastasis potential and prognosis of ovarian cancer.
结论:血浆DNA水平有可能成为辅助早期诊断卵巢恶性肿瘤、判断肿瘤侵袭转移情况和预测预后的指标之一。
Objective To detect the promoter methylation status of SFRP1 gene in tissue and plasma DNA of non-small cell lung cancer(NSCLC) patients and evaluate its correlation with clinicopathological features.
目的检测SFRP1基因在非小细胞肺癌(NSCLC)组织和血浆中的甲基化状态,分析其临床意义。
The cell is a fertilized egg, so you take a fertilized egg and you directly inject plasma DNA into the pronucleus, into one of the pronucleus--pronuclei.
供试细胞是受精卵,当你获得一枚受精卵,可以直接将胞质DNA注射到,它的一个原核中
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