Conclusion The lipid-lowering therapy with SXBXP and simvastatin could inhibit angiogenesis and degradation of extracellular matrix in the atherosclerotic plaque in the rabbit model.
结论麝香保心丸与辛伐他汀的治疗,可以抑制斑块内新生血管生长,减少斑块内胞外基质的降解,因此可能具有稳定粥样硬化斑块作用。
Unstable plaque which is vulnerable and prone to rupture has a thin fibrous cap with reduced extracellular matrix.
易破裂的不稳定性斑块中细胞外基质成分减少,斑块的纤维帽较薄,在外力的作用下易于破裂。
HO-1 expression levels correlated with the plaque destabilizing factors matrix metalloproteinase-9, interleukin-8, and interleukin-6.
HO - 1表达水平的高低与斑块不稳定因子-基质金属蛋白酶9,白介素8和白介素6具有相关性。
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