...吡柔比星(Pirarubicin)别称吡喃阿霉素(THP),是半合成的蒽环类抗癌药,通过直接嵌入DNA双螺旋链,抑制DNA聚合酶,阻止核酸合成,在G2期使细胞不能进行...
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Sumiyoshi等经狗髂动脉分叉处打针比柔吡星(Pirarubicin)l-2小时后,测得盆腔构造内药物浓度高于静脉路子的8倍,而其他构造内药物浓度两种要领相差不较着;②化疗药物起感化的部门首要为...
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Objective To evaluate the effect on prophase intravesical instillation of pirarubicin for preventing from recurrence of bladder cancer after transurethral bladder tumor resection(TURBT).
目的评估经尿道膀胱肿瘤电切(TURBT)术后吡柔比星早期膀胱灌注预防膀胱癌复发的疗效。
参考来源 - 吡柔比星早期灌注治疗预防膀胱癌复发的疗效观察Results:1 The inhibition of bortezomib and pirarubicin on the proliferation of Hut-78 cells.
结果:1硼替佐米、吡喃阿霉素单药对Hut-78细胞生长的抑制效应。
参考来源 - 硼替佐米与吡喃阿霉素序贯对T细胞淋巴瘤Hut·2,447,543篇论文数据,部分数据来源于NoteExpress
Myelosuppression was main toxicity of Pirarubicin, but alopecia was relatively slight and cardiac, liver, renal toxicity were mild.
吡喃阿霉素的毒性主要是骨髓抑制,但脱发率相对较低,心脏毒性、肝肾功能损害轻微。
The inhibition rate on K562/A02 cell line of Pirarubicin group was significantly higher than that of the same dose of Pharmorubicin or Daunorubicin (P<0.01).
吡喃阿霉素组对K562/A02细胞的抑制率较相同剂量表阿霉素组或柔红霉素组抑制率显著增加(P<0.01)。
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