In "Spore, " players make choices that evolve a creature from single cell--you cover the first 20 million years pretty quickly--to planet-hopping spaceship pilot, all with Pixar-quality cartoon brilliance of critters and landscape.
If you happen to be pilot on a trans-Atlantic flight, the consequences can be much more serious -- like mistaking the planet Venus for another plane and sending the plane you're piloting into a dive that slammed passengers into the ceiling and back to the floor.