Heterocycles containing the phthalazine ring are important targets in synthetic and medicinal chemistry, phthalazine derivatives, which have two bridgehead nitrogen atoms in a fused ring system, possess antimicrobial, anticonvulsant anticancer, vasorelaxant and anti-inflammatory activities.
在有机合成和药物化学中包含酞嗪环的分子是重要的目标化合物,酞嗪衍生物可用作抗菌剂、抗痉挛药。
参考来源 - 多化合物一锅反应的研究With PTK787 as the leading compound, some modifications were made at the 1 and 4 positions preserving the phthalazine ring .
以PTK787为先导化合物,在保留其活性酞嗪母环结构的基础上,对母环1位和4位进行结构修饰。
参考来源 - 苯胺酞嗪类化合物的设计及合成研究·2,447,543篇论文数据，部分数据来源于NoteExpress
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